RRAS

This article is about the human protein. For the Microsoft API and server software, see Routing and Remote Access Service.

Ras-related protein R-Ras is a protein that in humans is encoded by the RRAS gene.^[5][6]

RRAS
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2FN4
Identifiers
Aliases	RRAS, related RAS viral (r-ras) oncogene homolog, R-Ras, RAS related
External IDs	OMIM: 165090; MGI: 98179; HomoloGene: 4565; GeneCards: RRAS; OMA:RRAS - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.33 Start 49,635,292 bp[1] End 49,640,143 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 B3|7 29.08 cM Start 44,667,385 bp[2] End 44,671,071 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right coronary artery popliteal artery tibial arteries thoracic aorta ascending aorta Descending thoracic aorta left coronary artery gastric mucosa left uterine tube muscle layer of sigmoid colon Top expressed in tunica media of zone of aorta carotid body external carotid artery ascending aorta right lung white adipose tissue right lung lobe left lung aortic valve tunica adventitia of aorta More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GDP binding protein-containing complex binding GTP binding protein binding GTPase activity Cellular component membrane focal adhesion plasma membrane extracellular exosome intracellular anatomical structure Biological process positive regulation of angiogenesis negative regulation of cell migration regulation of protein kinase B signaling regulation of ERK1 and ERK2 cascade leukocyte differentiation Ras protein signal transduction face morphogenesis signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6237 20130 Ensembl ENSG00000126458 ENSMUSG00000038387 UniProt P10301 P10833 RefSeq (mRNA) NM_006270 NM_009101 NM_001360132 NM_001360133 RefSeq (protein) NP_006261 NP_033127 NP_001347061 NP_001347062 Location (UCSC) Chr 19: 49.64 – 49.64 Mb Chr 7: 44.67 – 44.67 Mb PubMed search [3] [4]
Wikidata
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Interactions

RRAS has been shown to interact with:

• ARAF,^[7][8]
• Bcl-2,^[9]
• NCK1,^[10]
• RALGDS,^[11] and
• RASSF5.^[12]