STX5

Syntaxin-5 is a protein that in humans is encoded by the STX5 gene.^[5][6][7]

STX5
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3EFO
Identifiers
Aliases	STX5, SED5, STX5A, syntaxin 5
External IDs	OMIM: 603189; MGI: 1928483; HomoloGene: 2381; GeneCards: STX5; OMA:STX5 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.3 Start 62,806,860 bp[1] End 62,832,051 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 8,718,777 bp[2] End 8,733,433 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow cells blood granulocyte body of pancreas olfactory zone of nasal mucosa canal of the cervix ectocervix left ovary left lobe of thyroid gland prostate Top expressed in primary oocyte internal carotid artery external carotid artery fossa condyle secondary oocyte lacrimal gland vas deferens pituitary gland islet of Langerhans More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein N-terminus binding protein binding SNARE binding SNAP receptor activity cadherin binding Cellular component integral component of membrane vesicle endoplasmic reticulum membrane membrane endoplasmic reticulum ER to Golgi transport vesicle membrane SNARE complex endoplasmic reticulum-Golgi intermediate compartment membrane Golgi apparatus cytosol Golgi membrane endomembrane system Biological process positive regulation of protein catabolic process vesicle fusion with Golgi apparatus early endosome to Golgi transport vesicle docking COPII vesicle coating regulation of Golgi organization retrograde transport, endosome to Golgi Golgi disassembly vesicle fusion vesicle-mediated transport intracellular protein transport endoplasmic reticulum to Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6811 56389 Ensembl ENSG00000162236 ENSMUSG00000010110 UniProt Q13190 Q8K1E0 RefSeq (mRNA) NM_001244666 NM_003164 NM_001330294 NM_001167799 NM_019829 RefSeq (protein) NP_001231595 NP_001317223 NP_003155 NP_001161271 NP_062803 Location (UCSC) Chr 11: 62.81 – 62.83 Mb Chr 19: 8.72 – 8.73 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

STX5 has been shown to interact with:

• BET1L,^[8][9]
• GOSR1,^{[8][10][11][12]}
• GOSR2,^[8][10][11]
• NAPA,^[13][14] and
• USO1.^[8][15]