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Zinc finger and BTB domain-containing protein 16

Protein found in humans From Wikipedia, the free encyclopedia

Zinc finger and BTB domain-containing protein 16
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Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.

Quick Facts ZBTB16, Available structures ...
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Function

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL)[5] and physiological roles have been identified in mouse Natural Killer T cells[6][7] and gamma-delta T cells.[8] Alternate transcriptional splice variants have been characterized in human.[9][10]

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Interactions

Zinc finger and BTB domain-containing protein 16 has been shown to interact with:

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See also

References

Further reading

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