5F-ADB-PINACA

Chemical compound From Wikipedia, the free encyclopedia

5F-ADB-PINACA

5F-ADB-PINACA is a cannabinoid designer drug that is an ingredient in some synthetic cannabis products. It is a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.24 nM and 2.1 nM respectively.[1][2]

Quick Facts Legal status, Identifiers ...
5F-ADB-PINACA
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Legal status
Legal status
Identifiers
  • N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H27FN4O2
Molar mass362.449 g·mol−1
3D model (JSmol)
  • CC(C)(C)[C@@H](C(=O)N)NC(=O)c1c2ccccc2n(n1)CCCCCF
  • InChI=1S/C19H27FN4O2/c1-19(2,3)16(17(21)25)22-18(26)15-13-9-5-6-10-14(13)24(23-15)12-8-4-7-11-20/h5-6,9-10,16H,4,7-8,11-12H2,1-3H3,(H2,21,25)(H,22,26)/t16-/m1/s1
  • Key:SOYDDJYBRCNNIT-MRXNPFEDSA-N
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Metabolism

Twelve 5F-ADB-PINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic reactions included oxidative defluorination followed by carboxylation.[3]

Legality

5F-ADB-PINACA is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.[4]

See also

References

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