Acidic leucine-rich nuclear phosphoprotein 32 family member A

Acidic leucine-rich nuclear phosphoprotein 32 family member A is a protein that in humans is encoded by the ANP32A gene.^[5][6][7] It is one of the targets of an oncomiR, MIRN21.

ANP32A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2JE0, 2JE1, 4XOS
Identifiers
Aliases	ANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32, acidic nuclear phosphoprotein 32 family member A
External IDs	OMIM: 600832; MGI: 108447; HomoloGene: 133783; GeneCards: ANP32A; OMA:ANP32A - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q23 Start 68,778,535 bp[1] End 68,820,897 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 B|9 33.68 cM Start 62,248,575 bp[2] End 62,286,094 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence ventricular zone monocyte paraflocculus of cerebellum middle frontal gyrus rectum blood C1 segment inferior ganglion of vagus nerve granulocyte Top expressed in neural layer of retina tail of embryo genital tubercle ventricular zone granulocyte maxillary prominence dentate gyrus of hippocampal formation granule cell mandibular prominence superior frontal gyrus migratory enteric neural crest cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding RNA binding histone binding Cellular component cytoplasm perinuclear region of cytoplasm endoplasmic reticulum nucleus nucleoplasm Biological process intracellular signal transduction regulation of transcription, DNA-templated nucleocytoplasmic transport transcription, DNA-templated regulation of mRNA stability nucleosome assembly regulation of apoptotic process histone exchange Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8125 11737 Ensembl ENSG00000140350 ENSMUSG00000032249 UniProt P39687 O35381 RefSeq (mRNA) NM_006305 NM_009672 RefSeq (protein) NP_006296 NP_033802 Location (UCSC) Chr 15: 68.78 – 68.82 Mb Chr 9: 62.25 – 62.29 Mb PubMed search [3] [4]
Wikidata
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Interactions

Acidic leucine-rich nuclear phosphoprotein 32 family member A has been shown to interact with MAP1B,^[8] TAF1A^[9] and Protein SET.^[9][10]

See also

• ANP32B, ANP32C, ANP32D, ANP32E