NEF3

Protein porodice sa domenom 3YTH je protein koji je kod ljudi kodiran genom YTHDF3.^[5][6]

NEF3
Identifikatori
Aliasi	YTHDF3
Vanjski ID-jevi	MGI: 1918850 HomoloGene: 34991 GeneCards: YTHDF3
Lokacija gena (čovjek) Hrom. Hromosom 8 (čovjek)[1] Bend 8q12.3 Početak 63,168,553 bp[1] Kraj 63,212,786 bp[1]
Lokacija gena (miš) Hrom. Hromosom 3 (miš)[2] Bend 3|3 A1 Početak 16,237,376 bp[2] Kraj 16,271,201 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • N6-methyladenosine-containing RNA binding • vezivanje sa RNK • ribosome binding Ćelijska komponenta • citoplazma • citosol Biološki proces • positive regulation of translation • positive regulation of translational initiation • mRNA destabilization Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	253943	229096
Ensembl	ENSG00000185728	ENSMUSG00000047213
UniProt	Q7Z739	Q8BYK6
RefSeq (mRNK)	NM_001277813 NM_001277814 NM_001277815 NM_001277816 NM_001277817 NM_001277818 NM_152758	NM_001145919 NM_172677 NM_001358041 NM_001358042 NM_001358043
RefSeq (bjelančevina)	NP_001264742 NP_001264743 NP_001264744 NP_001264745 NP_001264746 NP_001264747 NP_689971	NP_001139391 NP_766265 NP_001344970 NP_001344971 NP_001344972
Lokacija (UCSC)	Chr 8: 63.17 – 63.21 Mb	Chr 3: 16.24 – 16.27 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 585 aminokiselina, а molekulska težina 63.861 Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MSATSVDQRP		KGQGNKVSVQ		NGSIHQKDAV		NDDDFEPYLS		SQTNQSNSYP
PMSDPYMPSY		YAPSIGFPYS		LGEAAWSTAG		DQPMPYLTTY		GQMSNGEHHY
IPDGVFSQPG		ALGNTPPFLG		QHGFNFFPGN		ADFSTWGTSG		SQGQSTQSSA
YSSSYGYPPS		SLGRAITDGQ		AGFGNDTLSK		VPGISSIEQG		MTGLKIGGDL
TAAVTKTVGT		ALSSSGMTSI		ATNSVPPVSS		AAPKPTSWAA		IARKPAKPQP
KLKPKGNVGI		GGSAVPPPPI		KHNMNIGTWD		EKGSVVKAPP		TQPVLPPQTI
IQQPQPLIQP		PPLVQSQLPQ		QQPQPPQPQQ		QQGPQPQAQP		HQVQPQQQQL
QNRWVAPRNR		GAGFNQNNGA		GSENFGLGVV		PVSASPSSVE		VHPVLEKLKA
INNYNPKDFD		WNLKNGRVFI		IKSYSEDDIH		RSIKYSIWCS		TEHGNKRLDA
AYRSLNGKGP		LYLLFSVNGS		GHFCGVAEMK		SVVDYNAYAG		VWSQDKWKGK
FEVKWIFVKD		VPNNQLRHIR		LENNDNKPVT		NSRDTQEVPL		EKAKQVLKII
ATFKHTTSIF		DDFAHYEKRQ		EEEEAMRRER		NRNKQ

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