CHTF18

Chromosome transmission fidelity protein 18 homolog is a protein that in humans is encoded by the CHTF18 gene.^[5][6]

CHTF18
Identifiers
Aliases	CHTF18, C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL, chromosome transmission fidelity factor 18
External IDs	OMIM: 613201; MGI: 2384887; HomoloGene: 32532; GeneCards: CHTF18; OMA:CHTF18 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 788,046 bp[1] End 800,737 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 25,937,900 bp[2] End 25,946,393 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis mucosa of transverse colon right hemisphere of cerebellum pancreatic ductal cell gonad sural nerve ventricular zone ganglionic eminence granulocyte Top expressed in epiblast yolk sac internal carotid artery external carotid artery morula embryo blastocyst embryo ventricular zone neural layer of retina More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding DNA binding single-stranded DNA helicase activity protein binding ATP binding DNA clamp loader activity Cellular component membrane Ctf18 RFC-like complex nucleus nucleoplasm cytosol Biological process DNA replication cell cycle positive regulation of DNA-directed DNA polymerase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 63922 214901 Ensembl ENSG00000127586 ENSMUSG00000019214 UniProt Q8WVB6 Q8BIW9 RefSeq (mRNA) NM_022092 NM_145409 RefSeq (protein) NP_071375 NP_663384 Location (UCSC) Chr 16: 0.79 – 0.8 Mb Chr 17: 25.94 – 25.95 Mb PubMed search [3] [4]
Wikidata
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Interactions

CHTF18 has been shown to interact with:

• DCC1,^[7][8]
• PCNA,^[5]
• RFC2,^[7][8]
• RFC3,^[7][8]
• RFC4,^[7] and
• RFC5.^[7]