Top Qs
Timeline
Chat
Perspective

Enzyme-linked receptor

From Wikipedia, the free encyclopedia

Remove ads
Remove ads

An enzyme-linked receptor, also known as a catalytic receptor, is a transmembrane receptor, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side.[1] Hence a catalytic receptor is an integral membrane protein possessing both catalytic, and receptor functions.[2]

They have two important domains, an extra-cellular ligand binding domain and an intracellular domain, which has a catalytic function; and a single transmembrane helix. The signaling molecule binds to the receptor on the outside of the cell and causes a conformational change on the catalytic function located on the receptor inside the cell.

Examples of the enzymatic activity include:

Remove ads

Types

Summarize
Perspective

The following is a list of the five major families of catalytic receptors:

More information Family, Member ...
Remove ads

References

Loading content...
Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.

Remove ads