FBLN1

FBLN1
Identifikatori
Aliasi	FBLN1
Vanjski ID-jevi	OMIM: 135820 MGI: 95487 HomoloGene: 21295 GeneCards: FBLN1
Lokacija gena (čovjek)
Hrom.	Hromosom 22 (čovjek)
Kraj	45,601,135 bp
Lokacija gena (miš)
Hrom.	Hromosom 15 (miš)
Kraj	85,170,736 bp
Obrazac RNK ekspresije
	; ; ; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• fibronectin binding; • calcium ion binding; • extracellular matrix structural constituent; • fibrinogen binding; • integrin binding; • protein C-terminus binding; • GO:0001948, GO:0016582 vezivanje za proteine; • vezivanje identičnih proteina; • peptidase activator activity; • GO:0032403 protein-containing complex binding;
Ćelijska komponenta	• elastic fiber; • GO:0005578 Vanćelijski matriks; • Fibrinogen; • basement membrane; • Egzosom; • Vanćelijsko; • extracellular region; • collagen-containing extracellular matrix;
Biološki proces	• GO:0033128 negative regulation of protein phosphorylation; • negative regulation of cell adhesion; • negative regulation of stem cell proliferation; • positive regulation of fibroblast proliferation; • positive regulation of substrate-dependent cell migration, cell attachment to substrate; • negative regulation of cell motility; • negative regulation of transformation of host cell by virus; • positive regulation of peptidase activity; • GO:1901313 positive regulation of gene expression; • negative regulation of ERK1 and ERK2 cascade; • integrin-mediated signaling pathway; • blood coagulation, fibrin clot formation; • negative regulation of substrate adhesion-dependent cell spreading; • GO:0022415 viral process; • embryo implantation; • extracellular matrix organization;
	Izvori:Amigo / QuickGO
Ortolozi
	2192
	14114
	ENSG00000077942
	ENSMUSG00000006369
	P23142
	Q08879
	NM_006487; NM_001996; NM_006485; NM_006486
	NM_010180; NM_001347088
	NP_001987; NP_006476; NP_006477; NP_006478
	NP_001334017; NP_034310
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

FBLN1 je gen koji je kod ljudi lociran na hromosomu 22. Kodira fibulin-1, vanćelijski plazmatski protein.^[5]^[6]^[7]

Kratke činjenice Identifikatori, Aliasi ...

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10	20	30	40	50
MERAAPSRRV	PLPLLLLGGL	ALLAAGVDAD	VLLEACCADG	HRMATHQKDC
SLPYATESKE	CRMVQEQCCH	SQLEELHCAT	GISLANEQDR	CATPHGDNAS
LEATFVKRCC	HCCLLGRAAQ	AQGQSCEYSL	MVGYQCGQVF	QACCVKSQET
GDLDVGGLQE	TDKIIEVEEE	QEDPYLNDRC	RGGGPCKQQC	RDTGDEVVCS
CFVGYQLLSD	GVSCEDVNEC	ITGSHSCRLG	ESCINTVGSF	RCQRDSSCGT
GYELTEDNSC	KDIDECESGI	HNCLPDFICQ	NTLGSFRCRP	KLQCKSGFIQ
DALGNCIDIN	ECLSISAPCP	IGHTCINTEG	SYTCQKNVPN	CGRGYHLNEE
GTRCVDVDEC	APPAEPCGKG	HRCVNSPGSF	RCECKTGYYF	DGISRMCVDV
NECQRYPGRL	CGHKCENTLG	SYLCSCSVGF	RLSVDGRSCE	DINECSSSPC
SQECANVYGS	YQCYCRRGYQ	LSDVDGVTCE	DIDECALPTG	GHICSYRCIN
IPGSFQCSCP	SSGYRLAPNG	RNCQDIDECV	TGIHNCSINE	TCFNIQGGFR
CLAFECPENY	RRSAATLQQE	KTDTVRCIKS	CRPNDVTCVF	DPVHTISHTV
ISLPTFREFT	RPEEIIFLRA	ITPPHPASQA	NIIFDITEGN	LRDSFDIIKR
YMDGMTVGVV	RQVRPIVGPF	HAVLKLEMNY	VVGGVVSHRN	VVNVHIFVSE
YWF

FBLN1

Aminokiselinska sekvenca

Struktura

Funkcija

Interakcije

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Reference

Dopunska literatura

Vanjski linkovi

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