LRRC15

Protein 15 sa leucinom bogatim ponavljanjem jest protein koji je kod ljudi kodiran genom LRRC15 sa hromosoma 3.^[5]

LRRC15
Identifikatori
Aliasi	LRRC15
Vanjski ID-jevi	MGI: 1921738 HomoloGene: 26080 GeneCards: LRRC15
Lokacija gena (čovjek) Hrom. Hromosom 3 (čovjek)[1] Bend 3q29 Početak 194,355,249 bp[1] Kraj 194,369,743 bp[1]
Lokacija gena (miš) Hrom. Hromosom 16 (miš)[2] Bend 16|16 B2 Početak 30,088,120 bp[2] Kraj 30,102,074 bp[2]
Ontologija gena Molekularna funkcija • fibronectin binding • protein kinase inhibitor activity • laminin binding • collagen binding Ćelijska komponenta • citoplazma • integral component of membrane • Egzosom • membrana • Vanćelijsko • GO:0005578 Vanćelijski matriks • collagen-containing extracellular matrix Biološki proces • negative regulation of protein kinase activity • cytokine-mediated signaling pathway • negative regulation of receptor signaling pathway via JAK-STAT • positive regulation of cell migration • negative regulation of protein localization to plasma membrane Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	131578	74488
Ensembl	ENSG00000172061	ENSMUSG00000052316
UniProt	Q8TF66	Q80X72
RefSeq (mRNK)	NM_130830 NM_001135057	NM_028973
RefSeq (bjelančevina)	NP_001128529 NP_570843	NP_083249
Lokacija (UCSC)	Chr 3: 194.36 – 194.37 Mb	Chr 16: 30.09 – 30.1 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 581 aminokiselina, а molekulska težina 64.366 Da.^[6].

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MPLKHYLLLL		VGCQAWGAGL		AYHGCPSECT		CSRASQVECT		GARIVAVPTP
LPWNAMSLQI		LNTHITELNE		SPFLNISALI		ALRIEKNELS		RITPGAFRNL
GSLRYLSLAN		NKLQVLPIGL		FQGLDSLESL		LLSSNQLLQI		QPAHFSQCSN
LKELQLHGNH		LEYIPDGAFD		HLVGLTKLNL		GKNSLTHISP		RVFQHLGNLQ
VLRLYENRLT		DIPMGTFDGL		VNLQELALQQ		NQIGLLSPGL		FHNNHNLQRL
YLSNNHISQL		PPSVFMQLPQ		LNRLTLFGNS		LKELSPGIFG		PMPNLRELWL
YDNHISSLPD		NVFSNLRQLQ		VLILSRNQIS		FISPGAFNGL		TELRELSLHT
NALQDLDGNV		FRMLANLQNI		SLQNNRLRQL		PGNIFANVNG		LMAIQLQNNQ
LENLPLGIFD		HLGKLCELRL		YDNPWRCDSD		ILPLRNWLLL		NQPRLGTDTV
PVCFSPANVR		GQSLIIINVN		VAVPSVHVPE		VPSYPETPWY		PDTPSYPDTT
SVSSTTELTS		PVEDYTDLTT		IQVTDDRSVW		GMTQAQSGLA		IAAIVIGIVA
LACSLAACVG		CCCCKKRSQA		VLMQMKAPNE		C