PBX1

PBX1
Dostupne strukture
PDB	Pretraga ortologa: PDBe RCSB
Spisak PDB ID kodova
	1B72, 1PUF
Identifikatori
Aliasi	PBX1
Vanjski ID-jevi	OMIM: 176310 MGI: 97495 HomoloGene: 20574 GeneCards: PBX1
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	164,899,296 bp
Lokacija gena (miš)
Hrom.	Hromosom 1 (miš)
Kraj	168,259,839 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• sequence-specific DNA binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • protein heterodimerization activity; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • vezivanje sa DNK; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • transcription factor binding; • GO:0001948, GO:0016582 vezivanje za proteine; • RNA polymerase II transcription regulatory region sequence-specific DNA binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• citoplazma; • jedro; • transcription regulator complex; • nukleoplazma; • RNA polymerase II transcription regulator complex;
Biološki proces	• anterior/posterior pattern specification; • proximal/distal pattern formation; • positive regulation of G2/M transition of mitotic cell cycle; • embryonic organ development; • embryonic hemopoiesis; • negative regulation of DNA-binding transcription factor activity; • transcription, DNA-templated; • sex differentiation; • multicellular organism development; • embryonic limb morphogenesis; • somatic stem cell population maintenance; • regulation of cell population proliferation; • adrenal gland development; • spleen development; • thymus development; • positive regulation of cell population proliferation; • urogenital system development; • GO:0009373 regulation of transcription, DNA-templated; • regulation of ossification; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • transcription by RNA polymerase II; • negative regulation of neuron differentiation; • embryonic skeletal system development; • branching involved in ureteric bud morphogenesis; • steroid biosynthetic process; • Ćelijska diferencijacija; • animal organ morphogenesis; • positive regulation of transcription of Notch receptor target;
	Izvori:Amigo / QuickGO
Ortolozi
	5087
	18514
	ENSG00000185630
	ENSMUSG00000052534
	P40424
	P41778
	NM_001204961; NM_001204963; NM_002585; NM_001353130; NM_001353131
	NM_001291508; NM_001291509; NM_008783; NM_183355
	NP_001191890; NP_001191892; NP_002576; NP_001340059; NP_001340060
	NP_001278437; NP_001278438; NP_032809; NP_899198
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Pre-B-ćelijski leukemijski transkripcijski faktor 1 jest protein koji je kod ljudi kodiran genom PBX1 sa hromosoma 1.^[5]

Kratke činjenice Dostupne strukture, PDB ...

[5]

[1]

[2]

[3]

[4]

10	20	30	40	50
MDEQPRLMHS	HAGVGMAGHP	GLSQHLQDGA	GGTEGEGGRK	QDIGDILQQI
MTITDQSLDE	AQARKHALNC	HRMKPALFNV	LCEIKEKTVL	SIRGAQEEEP
TDPQLMRLDN	MLLAEGVAGP	EKGGGSAAAA	AAAAASGGAG	SDNSVEHSDY
RAKLSQIRQI	YHTELEKYEQ	ACNEFTTHVM	NLLREQSRTR	PISPKEIERM
VSIIHRKFSS	IQMQLKQSTC	EAVMILRSRF	LDARRKRRNF	NKQATEILNE
YFYSHLSNPY	PSEEAKEELA	KKCGITVSQV	SNWFGNKRIR	YKKNIGKFQE
EANIYAAKTA	VTATNVSAHG	SQANSPSTPN	SAGSSSSFNM	SNSGDLFMSV
QSLNGDSYQG	AQVGANVQSQ	VDTLRHVISQ	TGGYSDGLAA	SQMYSPQGIS
ANGGWQDATT	PSSVTSPTEG	PGSVHSDTSN

PBX1

Aminokiselinska sekvenca

Interakcije

Reference

Dopunska literatura

Vanjski linkovi

Wikiwand - on