PSAPL1

Polipeptidoliki proaktivator 1 jest protein koji je kod ljudi kodiran genom PSAPL1 sa hromosoma 4. Član je proteinske porodice sapozina. ^[5]

PSAPL1
Identifikatori
Aliasi	PSAPL1
Vanjski ID-jevi	MGI: 1924193 HomoloGene: 105928 GeneCards: PSAPL1
Lokacija gena (čovjek) Hrom. Hromosom 4 (čovjek)[1] Bend 4p16.1 Početak 7,430,285 bp[1] Kraj 7,434,930 bp[1]
Lokacija gena (miš) Hrom. Hromosom 5 (miš)[2] Bend 5|5 B3 Početak 36,361,365 bp[2] Kraj 36,363,912 bp[2]
Ontologija gena Molekularna funkcija • GO:0010577 enzyme activator activity • G protein-coupled receptor binding Ćelijska komponenta • extracellular region • Lizozom • Vanćelijsko • citoplazma • citosol Biološki proces • regulation of lipid metabolic process • prostate gland growth • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • epithelial cell differentiation involved in prostate gland development • sphingolipid metabolic process • lipid metabolism • GO:0048554 positive regulation of catalytic activity Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	768239	76943
Ensembl	ENSG00000178597	ENSMUSG00000043430
UniProt	Q6NUJ1	Q8C1C1
RefSeq (mRNK)	NM_001085382	NM_175249
RefSeq (bjelančevina)	NP_001078851	NP_780458
Lokacija (UCSC)	Chr 4: 7.43 – 7.43 Mb	Chr 5: 36.36 – 36.36 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 521 aminokiselina, а molekulska težina 56.627 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MLCALLLLPS		LLGATRASPT		SGPQECAKGS		TVWCQDLQTA		ARCGAVGYCQ
GAVWNKPTAK		SLPCDVCQDI		AAAAGNGLNP		DATESDILAL		VMKTCEWLPS
QESSAGCKWM		VDAHSSAILS		MLRGAPDSAP		AQVCTALSLC		EPLQRHLATL
RPLSKEDTFE		AVAPFMANGP		LTFHPRQAPE		GALCQDCVRQ		VSRLQEAVRS
NLTLADLNIQ		EQCESLGPGL		AVLCKNYLFQ		FFVPADQALR		LLPPQELCRK
GGFCEELGAP		ARLTQVVAMD		GVPSLELGLP		RKQSEMQMKA		GVTCEVCMNV
VQKLDHWLMS		NSSELMITHA		LERVCSVMPA		SITKECIILV		DTYSPSLVQL
VAKITPEKVC		KFIRLCGNRR		RARAVHDAYA		IVPSPEWDAE		NQGSFCNGCK
RLLTVSSHNL		ESKSTKRDIL		VAFKGGCSIL		PLPYMIQCKH		FVTQYEPVLI
ESLKDMMDPV		AVCKKVGACH		GPRTPLLGTD		QCALGPSFWC		RSQEAAKLCN
AVQHCQKHVW		KEMHLHAGEH		A