LDB2

Protein 2 sa vezujućim domenom LIM jest protein koji je kod ljudi kodiran genom LDB2 sa hromosoma 4.^[5][6][7][8]

LDB2
Identifikatori
Aliasi	LDB2
Vanjski ID-jevi	OMIM: 603450 MGI: 894670 HomoloGene: 989 GeneCards: LDB2
Lokacija gena (čovjek) Hrom. Hromosom 4 (čovjek)[1] Bend 4p15.32 Početak 16,501,541 bp[1] Kraj 16,898,678 bp[1]
Lokacija gena (miš) Hrom. Hromosom 5 (miš)[2] Bend 5|5 B3 Početak 44,629,474 bp[2] Kraj 44,957,022 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • vezivanje enzima • LIM domain binding • GO:0001104 transcription coregulator activity • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • jedro • transcription regulator complex • cell leading edge • Jedarce • ćelijska membrana Biološki proces • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • hair follicle development • positive regulation of cellular component biogenesis • epithelial structure maintenance • somatic stem cell population maintenance • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • regulation of kinase activity • regulation of cell migration • GO:1901227 negative regulation of transcription by RNA polymerase II • multicellular organism development • GO:0045996 negative regulation of transcription, DNA-templated Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	9079	16826
Ensembl	ENSG00000169744	ENSMUSG00000039706
UniProt	O43679	O55203
RefSeq (mRNK)	NM_001130834 NM_001290 NM_001304434 NM_001304435	NM_001077398 NM_001286348 NM_010698 NM_001347349 NM_001359070 NM_001359071
RefSeq (bjelančevina)	NP_001124306 NP_001281 NP_001291363 NP_001291364	NP_001070866 NP_001273277 NP_001334278 NP_034828 NP_001345999 NP_001346000
Lokacija (UCSC)	Chr 4: 16.5 – 16.9 Mb	Chr 5: 44.63 – 44.96 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 373 aminokiseline, а molekulska težina 42.793 Da.^[9]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MSSTPHDPFY		SSPFGPFYRR		HTPYMVQPEY		RIYEMNKRLQ		SRTEDSDNLW
WDAFATEFFE		DDATLTLSFC		LEDGPKRYTI		GRTLIPRYFS		TVFEGGVTDL
YYILKHSKES		YHNSSITVDC		DQCTMVTQHG		KPMFTKVCTE		GRLILEFTFD
DLMRIKTWHF		TIRQYRELVP		RSILAMHAQD		PQVLDQLSKN		ITRMGLTNFT
LNYLRLCVIL		EPMQELMSRH		KTYNLSPRDC		LKTCLFQKWQ		RMVAPPAEPT
RQPTTKRRKR		KNSTSSTSNS		SAGNNANSTG		SKKKTTAANL		SLSSQVPDVM
VVGEPTLMGG		EFGDEDERLI		TRLENTQYDA		ANGMDDEEDF		NNSPALGNNS
PWNSKPPATQ		ETKSENPPPQ		ASQ