MAML3

Upravljački protein 3 (Drosophila) je protein koji je kod ljudi kodiran genom MAML3 sa hromosoma 4.^[5]

MAML3
Identifikatori
Aliasi	MAML3
Vanjski ID-jevi	OMIM: 608991 MGI: 2389461 HomoloGene: 41284 GeneCards: MAML3
Lokacija gena (čovjek) Hrom. Hromosom 4 (čovjek)[1] Bend 4q31.1 Početak 139,716,753 bp[1] Kraj 140,154,184 bp[1]
Lokacija gena (miš) Hrom. Hromosom 3 (miš)[2] Bend 3|3 C Početak 51,593,328 bp[2] Kraj 52,012,497 bp[2]
Ontologija gena Molekularna funkcija • GO:0001105 transcription coactivator activity Ćelijska komponenta • jedro • nukleoplazma • nuclear speck Biološki proces • Notch signaling pathway • transcription initiation from RNA polymerase II promoter • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of transcription of Notch receptor target • positive regulation of Notch signaling pathway Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	55534	433586
Ensembl	ENSG00000196782	ENSMUSG00000061143
UniProt	Q96JK9	n/a
RefSeq (mRNK)	NM_018717	NM_001004176
RefSeq (bjelančevina)	NP_061187	n/a
Lokacija (UCSC)	Chr 4: 139.72 – 140.15 Mb	Chr 3: 51.59 – 52.01 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 1.138 aminokiselina, a molekulska težina 122.293 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MGDFAAPAAA		ANGSSICINS		SLNSSLGGAG		IGVNNTPNST		PAAPSSNHPA
AGGCGGSGGP		GGGSAAVPKH		STVVERLRQR		IEGCRRHHVN		CENRYQQAQV
EQLELERRDT		VSLYQRTLEQ		RAKKSGAGTG		KQQHPSKPQQ		DAEAASAEQR
NHTLIMLQET		VKRKLEGARS		PLNGDQQNGA		CDGNFSPTSK		RIRKDISAGM
EAINNLPSNM		PLPSASPLHQ		LDLKPSLPLQ		NSGTHTPGLL		EDLSKNGRLP
EIKLPVNGCS		DLEDSFTILQ		SKDLKQEPLD		DPTCIDTSET		SLSNQNKLFS
DINLNDQEWQ		ELIDELANTV		PEDDIQDLFN		EDFEEKKEPE		FSQPATETPL
SQESASVKSD		PSHSPFAHVS		MGSPQARPSS		SGPPFSTVST		ATSLPSVAST
PAAPNPASSP		ANCAVQSPQT		PNQAHTPGQA		PPRPGNGYLL		NPAAVTVAGS
ASGPVAVPSS		DMSPAEQLKQ		MAAQQQQRAK		LMQQKQQQQQ		QQQQQQQQQQ
QQQQQQQQQQ		HSNQTSNWSP		LGPPSSPYGA		AFTAEKPNSP		MMYPQAFNNQ
NPIVPPMANN		LQKTTMNNYL		PQNHMNMINQ		QPNNLGTNSL		NKQHNILTYG
NTKPLTHFNA		DLSQRMTPPV		ANPNKNPLMP		YIQQQQQQQQ		QQQQQQQQQQ
PPPPQLQAPR		AHLSEDQKRL		LLMKQKGVMN		QPMAYAALPS		HGQEQHPVGL
PRTTGPMQSS		VPPGSGGMVS		GASPAGPGFL		GSQPQAAIMK		QMLIDQRAQL
IEQQKQQFLR		EQRQQQQQQQ		QQILAEQQLQ		QSHLPRQHLQ		PQRNPYPVQQ
VNQFQGSPQD		IAAVRSQAAL		QSMRTSRLMA		QNAGMMGIGP		SQNPGTMATA
AAQSEMGLAP		YSTTPTSQPG		MYNMSTGMTQ		MLQHPNQSGM		SITHNQAQGP
RQPASGQGVG		MVSGFGQSML		VNSAITQQHP		QMKGPVGQAL		PRPQAPPRLQ
SLMGTVQQGA		QSWQQRSLQG		MPGRTSGELG		PFNNGASYPL		QAGQPRLTKQ
HFPQGLSQSV		VDANTGTVRT		LNPAAMGRQM		MPSLPGQQGT		SQARPMVMSG
LSQGVPGMPA		FSQPPAQQQI		PSGSFAPSSQ		SQAYERNAPQ		DVSYNYSGDG
AGGSFPGLPD		GADLVDSIIK		GGPGDEWMQE		LDELFGNP