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List of combined sex-hormonal preparations
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This is a list of known combined sex-hormonal formulations. Brand names and developmental code names are in parentheses.
Androgens
Injection
Marketed
- Nandrolone decanoate/nandrolone phenylpropionate (Dinandrol)
- Testosterone propionate/testosterone isocaproate/testosterone caproate (Androteston PP)[1]
- Testosterone propionate/testosterone enanthate/testosterone undecylenate (Durasteron)
- Testosterone propionate/testosterone enanthate (Testoviron Depot)
- Testosterone propionate/testosterone ketolaurate (Testosid Depot)
- Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (Sustanon 100)
- Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone caproate (Omnadren 250)
- Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate (Sustanon 250)
- Testosterone propionate/testosterone valerate/testosterone undecylenate (Triolandren)
- Testosterone propionate/testosterone cypionate/prasterone (Sten)
Veterinary
Marketed
- Boldenone acetate/boldenone cypionate/boldenone propionate/boldenone undecylenate (Equilon 100)
- Testosterone acetate/testosterone undecanoate/testosterone valerate (Deposterona)
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Estrogens
Oral
Marketed
- Conjugated estriol (Emmenin, Progynon)
- Conjugated estrogens (Premarin)
- Esterified estrogens (Estratab, Menest)
- Estradiol/estrone/estriol (Hormonin)
- Ethinylestradiol/dienestrol (Foxinette)
Injection
Marketed
- Estradiol benzoate/estradiol phenylpropionate (Dimenformon Prolongatum)
Never marketed
Progestogens
Injection
Marketed
Androgens and estrogens
Oral
Marketed
- Chlorotrianisene/methyltestosterone (Tace mit Androgen)[1]
- Conjugated estrogens/methyltestosterone (Premarin with Methyltestosterone)
- Dienestrol/methyltestosterone (Estan, Lucidon)
- Dienestrol diacetate/methyltestosterone (Farmatest)
- Diethylstilbestrol/methyltestosterone (Tylosterone)
- Esterified estrogens/methyltestosterone (Covaryx, Eemt, Essian, Estratest, Menogen, Syntest)
- Ethinylestradiol/methyltestosterone (Climatone, Dumone, Duotrone, Estandron, Femandren, Femovirin, Gynetone, Lynandron, Mepilin, Mixogen, Primodian)[1][2]
- Methylestradiol/methyltestosterone (Klimanosid)[2]
- Methylestradiol/methyltestosterone/reserpine (Klimanosid R)[1]
Injection
Marketed
- Estradiol benzoate/testosterone propionate (Bothermon)
- Estradiol benzoate/estradiol dienanthate/testosterone enanthate benzilic acid hydrazone (Climacteron, Lactimex, Lactostat)
- Estradiol benzoate/estradiol phenylpropionate/testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (Estandron Prolongatum, Lynandron Prolongatum, Mixogen [Injection])
- Estradiol benzoate/testosterone isobutyrate (Femandren M, Folivirin)
- Estradiol butyrylacetate/testosterone ketolaurate/reserpine (Klimanosid R-Depot)
- Estradiol cypionate/testosterone cypionate (Depo-Testadiol, Femovirin)
- Estradiol cypionate/testosterone enanthate (Supligol)
- Estradiol valerate/prasterone enanthate (Binodian Depot, Cidodian Depot, Gynodian Depot, Klimax, Supligol NF)
- Estradiol valerate/testosterone enanthate (Deladumone, Despamen, Ditate, Ditate-DS, Gravignost, Primodian Depot, Valertest)
Veterinary
Marketed
- Diethylstilbestrol/methyltestosterone (Maxymin, Tylosterone)
- Diethylstilbestrol/testosterone (Rapigain)
- Estradiol benzoate/estradiol enanthate/testosterone enanthate (Uni-Bol)
- Estradiol benzoate/testosterone propionate (Component E-H, Implix BF, Progro H, Synovex H)
- Ethinylestradiol/methyltestosterone (Taril)
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Estrogens and progestogens
Summarize
Perspective
Oral
Marketed
- Drospirenone/estetrol (Nextstellis, Drovelis, Lydisilka)
- Estradiol/nomegestrol acetate (Naemis, Zoely)
- Estradiol valerate/cyproterone acetate (Femilar)
- Estradiol valerate/dienogest (Natazia, Qlaira)
- Ethinylestradiol/chlormadinone acetate (Belara)[3]
- Ethinylestradiol/cyproterone acetate (Diane, Diane-35)
- Ethinylestradiol/desogestrel (Alenvona, Apri,[4] Azurette,[5] Bekyree,[6] Bimizza,[7] Caziant,[8] Cesia,[9] Cimizt,[10] Cyclessa,[11] Cyred,[12] Denise, Desogen,[13] Desirett, Emoquette,[14] Enskyce,[15] Gedarel, Gracial, Isibloom,[16] Juleber,[17] Kalliga, Kariva,[18] Kimidess,[19] Laurina, Linessa, Marvelon,[20][21][22] Mercilon,[23][24] Mircette,[25] Mirvala, Novynette, Ortho-Cept,[26] Pimtrea,[27] Reclipsen,[28] Regulon, Simliya,[29] Solia, Velivet,[30] Viorele,[31] Volnea[32])
- Ethinylestradiol/dienogest (Valette)
- Ethinylestradiol/dimethisterone (Oracon)
- Ethinylestradiol/drospirenone (Yasmin, Yasminelle, Yaz)
- Ethinylestradiol/drospirenone/levomefolic acid (Beyaz, Safyral)
- Ethinylestradiol/etynodiol diacetate (Demulen)
- Ethinylestradiol/gestodene (Femodene, Femodette, Gynera, Harmonet, Meliane, Minesse, Minulet)
- Ethinylestradiol/levonorgestrel (Amethyst, Aviane, Balcoltra, Falmina, Levlen, Lillow, Orsythia, Vienva)
- Ethinylestradiol/levonorgestrel/bisglycinate
- Ethinylestradiol/levonorgestrel/ferrous fumarate
- Ethinylestradiol/lynestrenol (Lyndiol)
- Ethinylestradiol/medroxyprogesterone acetate (Gianda, Provest)
- Ethinylestradiol/megestrol acetate (Nuvacon, Volidan)
- Ethinylestradiol/norethisterone (Brevicon, Norinyl 1+35, Ortho-Novum 7/7/7, Taytulla, Tri-Norinyl, Zenchent)
- Ethinylestradiol/norethisterone/ferrous fumarate (Blisovi 24 FE, Estrostep Fe, Femcon FE, Kaitlib FE, Lo Minastrin Fe, Loestrin 24 Fe, Microgestin 24 FE)
- Ethinylestradiol/norethisterone acetate (FemHRT)
- Ethinylestradiol/norethisterone acetate/ferrous fumarate
- Ethinylestradiol/norgestimate (Ortho Tri-Cyclen, Sprintec)
- Ethinylestradiol/norgestrel (Ovral)
- Ethinylestradiol/norgestrienone (Miniplanor, Planor)
- Ethinylestradiol/quingestanol acetate (Riglovis)
- Ethinylestradiol sulfonate/norethisterone acetate (Deposiston)
- Mestranol/anagestone acetate (Neo-Novum)
- Mestranol/chlormadinone acetate (C-Quens, Lutedion)
- Mestranol/etynodiol diacetate (Ovulen)
- Mestranol/hydroxyprogesterone acetate (Hormolidin)
- Mestranol/lynestrenol (Lyndiol)
- Mestranol/norethisterone (Norethin, Noriday, Norinyl, Norquen, Ortho-Novum)
- Mestranol/noretynodrel (Enavid, Enovid)
- Quinestrol/etynodiol diacetate (Soluna)
- Quinestrol/levonorgestrel (Yuèkětíng, Àiyuè)
- Quinestrol/norgestrel (Compound Norgestrel)
- Quinestrol/quingestanol acetate (Unovis)
For menopausal hormone therapy and/or gynecological disorders:
- Conjugated estrogens/medrogestone (Presomen)
- Conjugated estrogens/medroxyprogesterone acetate (Prempro, Premphase)
- Conjugated estrogens/norgestrel (Prempak-C)
- Estradiol/drospirenone (Angeliq)
- Estradiol/dydrogesterone (Femoston)
- Estradiol/gestodene (Avaden, Avadene)
- Estradiol/levonorgestrel
- Estradiol/medroxyprogesterone acetate (Indivina, Tridestra)
- Estradiol/norethisterone acetate (Activella, Activelle, Cliane, Estalis, Eviana, Evorel, Kliogest, Novofem)
- Estradiol/norgestimate (Prefest)
- Estradiol/progesterone (Bijuva)
- Estradiol/trimegestone (Lovelle, Totelle)
- Estradiol valerate/cyproterone acetate (Climen, Climen 28)
- Estradiol valerate/estriol/levonorgestrel (CycloÖstrogynal)
- Estradiol valerate/levonorgestrel (Cyclo-Progynova N)
- Estradiol valerate/medroxyprogesterone acetate (Dilena, Divina, Divitren, Farludiol, Indivina, Sisare)
- Estradiol valerate/norethisterone (Climagest, Climesse)
- Estradiol valerate/norethisterone acetate (Cliovelle, Norestin, Trisequens)
- Estradiol valerate/norgestrel (Cyclacur, Cyclocur, Cyclo-Progynova, Postoval, Progyluton)
- Ethinylestradiol/ethisterone (Amenorone, Di-Pro, Duosterone, Menstrogen, Oracecron, Orasecron)[2][1]
- Mestranol/noretynodrel (Enovid)
Never or not yet marketed
- Estradiol/norethisterone (Netagen, Netagen 403)
Transdermal
Marketed
- Ethinylestradiol/norelgestromin (Evra, Ortho Evra, Xulane)
For menopausal hormone therapy:
- Estradiol/levonorgestrel (Climara Pro)
- Estradiol/norethisterone acetate (CombiPatch)
Vaginal
Marketed
In contraceptive vaginal rings:
- Ethinylestradiol/etonogestrel (Circlet, NuvaRing)
- Segesterone acetate/ethinylestradiol (Annovera)
Injection
Marketed
In combined injectable contraceptives:
- Estradiol/megestrol acetate (Mego-E, Chinese Injectable No. 2)
- Estradiol benzoate/estradiol valerate/hydroxyprogesterone caproate (Sin-Ol)
- Estradiol benzoate butyrate/algestone acetophenide (Redimen, Soluna, Unijab)
- Estradiol cypionate/hydroxyprogesterone caproate (Sinbios)
- Estradiol cypionate/medroxyprogesterone acetate (Cyclo-Provera, Cyclofem, Lunelle)
- Estradiol enanthate/algestone acetophenide (Anafertin, Deladroxate, Perlutan, Topasel, Yectames)
- Estradiol valerate/hydroxyprogesterone caproate (Chinese Injectable No. 1)
- Estradiol valerate/norethisterone enanthate (Mesigyna, Mesygest)
For menopausal hormone therapy, gynecological disorders, habitual abortion, and other indications:
- Estradiol/progesterone (Juvenum)
- Estradiol benzoate/hydroxyprogesterone caproate (Primosiston)
- Estradiol benzoate/progesterone (Duogynon, Sistocyclin)
- Estradiol dipropionate/hydroxyprogesterone caproate (EP Hormone Depot)
- Estradiol hemisuccinate/progesterone (Hosterona)
- Estradiol pivalate/progesterone (Estrotate with Progesterone)
- Estradiol valerate/hydroxyprogesterone caproate (Gravibinan, Gravibinon)
- Estrone/progesterone (Synergon)
Never marketed
In combined injectable contraceptives:
- Estradiol/progesterone (in microspheres and macrocrystalline aqueous suspension)
- Estradiol undecylate/norethisterone enanthate
- Estradiol valerate/megestrol acetate
- Estradiol valerate/methenmadinone caproate (Lutofollin)
- Polyestradiol phosphate/medroxyprogesterone acetate
- Additional preparations listed at Combined injectable birth control § Research
For other indications:
- Estradiol valerate/gestonorone caproate (SH-834, SH-8.0834)
Veterinary
Marketed
- Estradiol benzoate/progesterone (Component E-S, Implix BM, Synovex C, Synovex S)
- Estradiol valerate/norgestomet (Syncro-Mate-B)
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Androgens and progestogens
Oral
Marketed
- Methyltestosterone/ethisterone (Androgeston)[1]
Injection
Marketed
Veterinary
Marketed
- Danazol/megestrol acetate (Dogalact)
- Nandrolone decanoate/methandriol dipropionate (Filybol, Tribolin)
- Nandrolone phenylpropionate/methandriol dipropionate (RWR)
Estrogens, progestogens, and androgens
Oral
Marketed
- Methylestradiol/normethandrone (Ginecosid, Ginecoside, Mediol, Renodiol)
Not yet marketed
Sublingual
Marketed
Injection
Marketed
- Estradiol benzoate/progesterone/methandriol dipropionate (Progestandron)
- Estradiol benzoate/progesterone/testosterone propionate (Lukestra, Steratrin, Trihormonal, Trinestryl)[1][2][36]
- Estradiol benzoate/estradiol valerate/norethisterone acetate/testosterone enanthate (Ablacton)
- Estradiol dibutyrate/hydroxyprogesterone heptanoate/testosterone caproate (Triormon Depositum)
- Estradiol diundecylate/hydroxyprogesterone heptanoate/testosterone cyclohexylpropionate (Trioestrine Retard)
- Estradiol hexahydrobenzoate/hydroxyprogesterone caproate/testosterone hexahydrobenzoate (Trinestril AP)
- Estrone/progesterone/testosterone (Tristeron, Tristerone)[36]
Never marketed
- Estrapronicate/hydroxyprogesterone heptanoate/nandrolone undecanoate (Trophobolene, Trophoboline)
Veterinary
Marketed
- Estradiol/trenbolone acetate (Component, Compudose-G, Progro TE-H, Revalor, Synovex)
- Estradiol benzoate/trenbolone acetate (Synovex Choice, Synovex One, Synovex Plus, Synovex with Trenbolone Acetate)
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Miscellaneous
Oral
Marketed
- Conjugated estrogens/bazedoxifene (Duavee)
Never marketed
- Esterified estrogens/raloxifene
- Estradiol/raloxifene
Transdermal
Marketed
- Estradiol benzoate/prednisolone/salicylic acid (Alpicort E, Alpicort F, Alpicort Plus)
Vaginal
Marketed
- Estradiol benzoate/gentamicin/hydrocortisone/nystatin (Cridermol Fem, Ginabiot, Ginecovan)
- Estradiol benzoate/monalazone (Malun-25)
Mixed
Marketed
- Goserelin/bicalutamide (ZolaCos CP)
- Leuprorelin/norethisterone acetate (Lupaneta Pack)
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See also
References
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