List of psychedelic drugs

This is a list of psychedelic drugs, also known as serotonergic psychedelics or classical hallucinogens. These drugs act specifically as serotonin 5-HT_2A receptor agonists. They belong to three major structural families: the tryptamines, phenethylamines, and lysergamides.

The † symbol denotes compounds that are known to be naturally occurring.

Tryptamines

• Tryptamine (T)†
• N,N-Dimethyltryptamine†, also known as 'DMT'; the primary active constituent of the Amerindian brew ayahuasca; endogenously present in various plants and animals, including humans, possibly a trace amine neurotransmitter. NB-DMT might act as a prodrug of N,N-DMT
• N-Methyl-N-ethyltryptamine, also known as 'MET'
• N-Methyl-N-isopropyltryptamine, also known as 'MiPT'
• N-Methyl-N-propyltryptamine, also known as 'MPT'
• N,N-Diethyltryptamine, also known as 'DET'
• N-Ethyl-N-isopropyltryptamine, also known as 'EiPT'
• N-Methyl-N-butyltryptamine, also known as 'MBT'
• N-Propyl-N-isopropyltryptamine, also known as 'PiPT'
• N,N-Dipropyltryptamine, also known as 'DPT'
• N,N-Diisopropyltryptamine, also known as 'DiPT'
• N,N-Diallyltryptamine, also known as 'DALT'
• N,N-Dibutyltryptamine, also known as 'DBT'
• N-Ethyltryptamine, also known as 'NET'
• N-Methyltryptamine†, also known as 'NMT'; its psychedelic activity is disputed
• 5-Bromo-DMT†, was found in the marine invertebrates Smenospongia aurea and Smenospongia echina, as well as in Verongula rigida
• Trimethyltryptamine, also known as 'TMT' (2,N,N-TMT, 5,N,N-TMT, and 7,N,N-TMT)
• 5-MeS-DMT
• 5-Me-MiPT, its psychedelic activity is disputed
• 2-Me-DET
• 6-Fluoro-DMT

4-Hydroxytryptamines

• Psilocin†, also known as '4-HO-DMT'; another active constituent of the Psilocybe genus of mushrooms; also a metabolite of psilocybin and psilacetin
• Psilocybin†, also known as '4-PO-DMT'; the primary active constituent of the Psilocybe genus of mushrooms; its effects are partially attributed to psilocin, to which it is a prodrug via dephosphorylation
• Baeocystin†, also known as '4-PO-NMT'; another active constituent of the Psilocybe genus of mushrooms; its psychedelic activity is disputed
• Aeruginascin†, also known as '4-PO-N-TMT', an active constituent of the mushroom Inocybe aeruginascens
• Ethocybin, also known as '4-PO-DET', 'CEY-19', and 'CEY-39'
• 4-HO-MET, also known as 'Metocin', 'Methylcybin', and 'Colour'
• 4-HO-DET, also known as 'Ethocin' and 'CZ-74'
• 4-HO-MPT, also known as 'Meprocin'
• 4-HO-MiPT, also known as 'Miprocin'
• 4-HO-MALT
• 4-HO-DPT, also known as 'Deprocin'
• 4-HO-DiPT, also known as 'Iprocin'
• 4-HO-DALT, also known as 'Daltocin'
• 4-HO-DBT
• 4-HO-DSBT
• 4-HO-MPMI, also known as 'Lucigenol'
• 4-HO-TMT
• O-4310, also known as '6-Fluoro-1-Isopropyl-4-HO-DMT'
• 4-HO-1,N,N-TMT, also known as '1-Me-4-HO-DMT' and '1-methylpsilocin'
• 4-HO-5-MeO-DMT, also known as 'Psilomethoxin'

4-Acetoxytryptamines

• 4-AcO-DMT, also known as 'psiloacetin'; its effects are partially attributed to psilocin, to which it is a prodrug via deacetylation
• 4-AcO-MET, also known as 'Metacetin'
• 4-AcO-MiPT
• 4-AcO-MALT
• 4-AcO-DET, also known as 'Ethacetin'
• 4-AcO-EiPT, also known as 'Ethipracetin'
• 4-AcO-DPT, also known as 'Depracetin'
• 4-AcO-DiPT, also known as 'Ipracetin'
• 4-AcO-DALT, also known as 'Daltacetin'

4-Methoxytryptamines

• 4-MeO-DMT
• 4-MeO-MiPT

5-Hydroxytryptamines

• Bufotenin†, also known as '5-HO-DMT' and dimethylserotonin; another constituent of the skin and venom of psychoactive toads, its psychedelic activity is disputed; also a metabolite of 5-MeO-DMT
• 5-HO-DET
• 5-HO-DPT
• 5-HO-DiPT

5-Methoxytryptamines

• 5-MeO-DMT†, the primary active constituent of the skin and venom of psychoactive toads, a prodrug to bufotenin via demethylation
• 5-MeO-NMT†
• 5-MeO-MET
• 5-MeO-MPT
• 5-MeO-MiPT, also known as 'Moxy'; also has entactogenic properties
• 5-MeO-MALT
• 5-MeO-DET
• 5-MeO-EiPT
• 5-MeO-EPT
• 5-MeO-PiPT
• 5-MeO-DPT
• 5-MeO-DiPT, also known as 'Foxy Methoxy'
• 5-MeO-DALT
• 4-F-5-MeO-DMT
• 4-HO-5-MeO-DMT, also known as 'Psilomethoxin'
• 5-MeO-2,N,N-TMT, also known as 'Indomethacin' and 'Indapex'
• 5-MeO-7,N,N-TMT

α-Alkyltryptamines

• α-Methyltryptamine, also known as 'αMT' and 'AMT'; also has entactogenic properties
• α-Ethyltryptamine, also known as 'αET' and 'AET'; also has entactogenic properties
• α,N-DMT
• α,N,N-Trimethyltryptamine, also known as 'α-TMT'
• 4-HO-αMT
• 5-MeO-αMT
• 5-MeO-αET
• 2,α-DMT
• 4-Me-αMT
• 4-Me-αET, also has entactogenic properties
• 7-Me-αET, also has entactogenic properties
• 5-Fluoro-αMT, also has entactogenic properties
• 6-Fluoro-αMT
• 5-MeO-α,N-DMT, also known as 'α,N,O-TMS'

Ring-extended tryptamines

• CP-132,484, also known as '4,5-DHP-1-Methyltryptamine'
• 4,5-DHP-DMT
• 4,5-DHP-AMT, also known as 'AL-37350A'
• 4,5-MDO-DMT
• 4,5-MDO-DiPT
• 5,6-MDO-DiPT
• 5,6-MDO-MiPT

Cyclized tryptamines

• N,N-Tetramethylenetryptamine, also known as 'Pyr-T'
• 4-HO-pyr-T
• 5-MeO-pyr-T
• 4-F-5-MeO-pyr-T
• RU-28306, also known as '4,α-Methylene-N,N-DMT'
• 5-MeO-MPMI

Phenethylamines

See also: Substituted methoxyphenethylamine

Scalines (4-substituted 3,5-dimethoxyphenethylamines and related)

• Mescaline†, the primary active constituent of certain cacti, such as peyote and San Pedro cactus
• Lophophine†, also known as 'MMDPEA'; another active constituent of certain cacti, such as peyote and the San Pedro cactus (Trichocereus macrogonus var. pachanoi, syn. Echinopsis pachanoi); also has entactogenic properties
• Isomescaline
• Cyclopropylmescaline
• Thioisomescaline (2-TIM, 3-TIM, and 4-TIM)
• 4-Desoxymescaline
• Escaline
• Metaescaline
• Thiometaescaline (3-TME, 4-TME, and 5-TME)
• Trisescaline
• Thiotrisescaline (3-T-TRIS and 4-T-TRIS)
• Symbescaline
• Asymbescaline
• Thiosymbescaline (3-TSB and 4-TSB)
• Phenescaline
• Allylescaline, also known as 'AL'
• Methallylescaline
• Proscaline
• Isoproscaline
• Metaproscaline
• Thioproscaline
• Buscaline
• Thiobuscaline
• α-ethylmescaline, also known as 'AEM'
• Propynyl
• BOM, also known as 'β-Methoxy-mescaline'
• β-D
• 4-D
• 4-Bromo-3,5-dimethoxyamphetamine

3Cs (4-substituted 3,5-dimethoxyphenethylamines and related)

• 3C-E
• 3C-P
• 3C-DFE
• 3C-BZ

2Cs (4-substituted 2,5-dimethoxyphenethylamines)

• βk-2C-B
• 2C-B
• 2C-C
• 2C-D
• 2C-E
• 2C-EF
• 2C-F
• 2C-G (2C-G-1, 2C-G-2, 2C-G-3, 2C-G-4, 2C-G-5, 2C-G-6, and 2C-G-N)
• 2C-H
• 2C-I
• 2C-iP
• 2C-N
• 2C-O
• 2C-O-4
• 2C-P
• 2C-SE
• 2C-T
• 2C-T-2
• 2C-T-4
• 2C-T-7
• 2C-T-8
• 2C-T-9
• 2C-T-13
• 2C-T-15
• 2C-T-16
• 2C-T-17
• 2C-T-19
• 2C-T-21
• 2C-TFM
• 2C-YN
• BOB, also known as 'β-Methoxy-2C-B'
• BOD, also known as 'β-Methoxy-2C-D'
• BOHD, also known as 'β-Hydroxy-2C-D'
• HOT-2
• HOT-7
• HOT-17

TWEETIOs

• 2CB-2EtO
• 2CB-5EtO
• 2CB-diEtO
• 2CD-2EtO
• 2CD-diEtO
• 2CD-5EtO
• 2CI-2EtO
• 2CT-5EtO
• 2CT-2-2EtO
• 2CT-2-5EtO
• 2CT-2-diEtO
• 2CT-4-2EtO
• 2CT-7-2EtO

DOx (4-substituted 2,5-dimethoxyamphetamines)

• DOAM
• DOB
• Meta-DOB
• Methyl-DOB
• DOBU
• DOC
• DOEF
• DOET, also known as 'DOE'
• DOI
• DOM, also known as 'STP'
• DON
• DOPR
• DOiPR
• DOT, also known as 'Aleph' (Aleph-2, Aleph-4, Aleph-6, and Aleph-7)
• DOTFM
• 2,5-dimethoxy-3,4-dimethylamphetamine, also known as 'Ganesha'; (G-3, G-4, G-5, and G-N)
• 4-methyl-2,5-dimethoxymethamphetamine, also known as 'Beatrice', 'MDO-D', and 'MDOM'
• IDNNA
• MEM
• MPM

4Cs (4-substituted 2,5-dimethoxy-α-ethylphenethylamines)

• Ariadne, also known as 'α-Et-DOM', '4C-D', and 'Dimoxamine'
• 4C-B

Ψ-PEAs (4-substituted 2,6-dimethoxyphenethylamines)

• Ψ-2C-DFMO (ψ-2C-O-35)
• Ψ-2C-T-4
• Ψ-DODFMO
• Ψ-DOM
• TMA-6 (Ψ-TMA-2)

Methylenedioxyphenethylamines

• FLEA, also known as 'MDHMA'
• MDPH
• MDMP
• DMMDA
• DMMDA-2
• 2,N-dimethyl-4,5-methylenedioxyamphetamine, also known as 'Madam-6'
• 2-Bromo-4,5-methylenedioxyamphetamine, also known as '6-Bromo-MDA'
• Ethyl-J, also known as 'EBDB'
• Methyl-J, also known as 'MDMB'
• Ethyl-K, also known as 'EBDP'
• Methyl-K, also known as 'MBDP' and 'UWA-91'
• MDAL
• MDBU
• MDBZ
• MDDM
• MDIP
• MDMEOET
• MDMEO
• MDOH, also known as 'MDH'
• MDHOET
• MDPL
• MDCPM
• MDPR
• EIDA
• MMDA, also known as '3-methoxy-MDA' (2T-MMDA-3a and 4T-MMDA-2)
• MMDA-2
• DiFMDA
• 5-Methyl-MDA

Benzofurans

• 5-APB
• 6-APB, also known as 'Benzofury'
• 5-APDB
• 6-APDB
• 5-MAPB
• 5-MAPDB
• 6-MAPDB, its psychedelic activity is disputed
• 6-MAPB
• 6-EAPB
• 5-EAPB
• F
• F-2
• F-22

FLY

• 2C-B-FLY
• 2C-B-BUTTERFLY
• Br-DragonFLY
• TFMFly

N-Benzylphenethylamines

NBOMe derivatives

• 2C-H-NBOMe, also known as '25H-NBOMe'
• 2C-C-NBOMe, also known as '25C-NBOMe'
• 2C-B-NBOMe, also known as '25B-NBOMe', 'M25B-NBOMe', 'BOM 2-CB', 'Cimbi-36', 'Nova', or 'New Nexus'
• 2C-I-NBOMe, also known as '25I-NBOMe', 'Cimbi-5', "Solaris", or "N-Bomb"
• 2C-TFM-NBOMe, also known as '25TFM-NBOMe'
• 2C-D-NBOMe, also known as '25D-NBOMe'
• 2C-G-NBOMe, also known as '25G-NBOMe'
• 2C-E-NBOMe, also known as '25E-NBOMe'
• 2C-P-NBOMe, also known as '25P-NBOMe'
• 2C-iP-NBOMe, also known as '25iP-NBOMe'
• 2C-CN-NBOMe, also known as '25CN-NBOMe'
• 2C-N-NBOMe, also known as '25N-NBOMe'
• 2C-T-NBOMe, also known as '25T-NBOMe'
• 2C-T-2-NBOMe, also known as '25T2-NBOMe'
• 2C-T-4-NBOMe, also known as '25T4-NBOMe'
• 2C-T-7-NBOMe, also known as '25T7-NBOMe'
• 2CBCB-NBOMe, also known as 'NBOMe-TCB-2'
• 2CBFly-NBOMe, also known as 'Cimbi-31'
• NBOMe-mescaline
• NBOMe-escaline
• 2C2-NBOMe, also known as 2C-MMDA-2-NBOMe or NBOMe-MMDPEA-2

NBOH derivatives

• 2C-C-NBOH, also known as '25C-NBOH' and 'NBOH-2CC'
• 2C-B-NBOH, also known as '25B-NBOH'
• 2C-I-NBOH, also known as '25I-NBOH'
• 2C-CN-NBOH, also known as '25CN-NBOH' and 'NBOH-2C-CN'

NBMD derivatives

• 2C-I-NBMD, also known as '25I-NBMD'

NBF derivatives

• 2C-C-NBF, also known as '25C-NBF'
• 2C-B-NBF, also known as '25B-NBF'
• 2C-I-NBF, also known as '25I-NBF'

Others/unsorted

• Dimethoxyamphetamine (DMA) (2,4-DMA, 2,5-DMA, and 3,4-DMA)
• Trimethoxyamphetamine (TMA) (TMA-2, TMA-6)
• Tetramethoxyamphetamine (TeMA)
• Norfenfluramine, also known as '3-TFMA'
• Para-Iodoamphetamine, also known as 'PIA', '4-iodoamphetamine', and '4-IA'
• Para-Chloroamphetamine, also known as 'PCA', '4-chloroamphetamine', and '4-CA'
• Macromerine
• MEPEA
• TOM (2-TOM and 5-TOM)
• Bis-TOM
• TOMSO, also known as '2-methoxy-4-methyl-5-methylsulfinylamphetamine'
• TOET (2-TOET and 5-TOET)
• BOH
• DME
• Meta-DOT
• Ortho-DOT
• EEE
• EEM
• EME
• EMM
• Para-Methoxyamphetamine, also known as 'PMA' and '4-MA'
• Paramethoxymethamphetamine, also known as 'PMMA', 'Methyl-MA', and '4-MMA'
• 4-Ethylamphetamine, also known as '4-EA'
• 3-Methoxy-4-methylamphetamine, also known as 'MMA'
• 4-Methylmethamphetamine, also known as '4-MMA'
• 4-Methylthioamphetamine, also known as '4-MTA'
• 4-Fluoroamphetamine, also known as '4-FA', 'PAL-303', 'Flux', 'Flits', 'R2D2', and 'Miley'
• Iris
• Methyl-DMA
• MEE
• MME

Cyclized phenethylamines

• Phenylcyclopropylamines
  • DMCPA
• Jimscaline
• Indanes
  • 2CB-Ind
• Benzocyclobutene derivatives (technically not phenethylamines)
  • 2C-BCB, also known as 'TCB-2'
• DMBMPP, 2-Benzylpiperidine analogue of 25B-NBOMe

Lysergamides

• Ergine, also known as lysergic acid amide (LSA); one of the primary active constituents of morning glory and Hawaiian baby woodrose seeds
• Isoergine, also known as isolysergic acid amide (iso-LSA); one of the primary active constituents of morning glory and Hawaiian baby woodrose seeds
• Lysergic acid diethylamide, also known as 'LSD' and 'acid'
• Lysergic acid ethylamide, also known as 'LAE-32'
• Lysergic acid α-hydroxyethylamide†, also known as 'LSH' and 'LAH'; another active constituent of morning glory seeds; an active constituent of some species of fungi
• Lysergic acid 2-butyl amide, also known as 'LSB'
• Lysergic acid 3-pentyl amide, also known as 'LSP'
• Lysergic acid methyl ester, also known as 'LSME'
• N,N-Dimethyl-lysergamide, also known as 'DAM-57'
• Methylisopropyllysergamide, also known as 'MIPLA'
• N,N-Diallyllysergamide, also known as 'DAL'
• Lysergic acid β-propanolamide†, also known as 'ergonovine' and 'ergometrine'; another active constituent of morning glory seeds, and an active constituent of ergot fungi
• Lysergic acid 1-butanolamide†, also known as 'Methylergonovine', 'Methergine', and 'Methylergometrine'; another active constituent of morning glory seeds and of ergot fungi

Amide-cyclized lysergamides

• Lysergic acid 2,4-dimethylazetidide, also known as 'LSZ' and 'LA-SS-Az'
• Lysergic acid piperidine, also known as 'LSD-Pip'; its psychedelic activity is disputed
• N-Pyrrolidyllysergamide, also known as 'LPD-824'
• N-Morpholinyllysergamide, also known as 'LSM-775'

1-Substituted lysergamides

• 1-methyl-lysergic acid butanolamide, also known as 'Methysergide'; the active constituent of Sansert and Deseril; a prodrug which has to be metabolized to methylergometrine to become psychoactive
• N1-Methyl-lysergic acid diethylamide, also known as 'MLD-41'
• N-Acetyl-lysergic acid diethylamide, also known as 'ALD-52'
• 1-Propionyl-lysergic acid diethylamide, also known as '1P-LSD'; its effects are partially attributed to LSD, to which it is a prodrug via hydrolyzation
• 1‐cyclopropanoyl‐d‐lysergic acid diethylamide, also known as '1cP-LSD'
• 1-valeryl-D-lysergic acid diethylamide, also known as '1V-LSD'

6-Substituted lysergamides

• 6-Allyl-6-nor-lysergic acid diethylamide, also known as 'AL-LAD'
• 6-Butyl-6-nor-lysergic acid diethylamide, also known as 'BU-LAD'
• 6-Ethyl-6-nor-lysergic acid diethylamide, also known as 'ETH-LAD'
• 1-Propionyl-6-Ethyl-6-nor-lysergic acid diethylamide, also known as '1P-ETH-LAD'
• 6-Propyl-6-nor-lysergic acid diethylamide, also known as 'PRO-LAD'
• 6-Cyclopropyl-6-nor-lysergic acid diethylamide, also known as 'CYP-LAD'
• 6-Propynyl-6-nor-lysergic acid diethylamide, also known as 'PARGY-LAD'

Others

Benzofurans

• Dimemebfe, also known as '5-MeO-BFE'
• 5-MeO-DiBF

Piperazines

• MK-212
• pFPP
• Quipazine
• TFMPP

Benzoxazines

• Efavirenz, the active constituent of Sustiva, Stocrin, and Efavir

See also

• List of drugs
• List of hallucinogens
• List of entheogens
• List of designer drugs
• Psychedelic plants
• PiHKAL and TiHKAL